Involvement of ST8SIA1 was supported in a second study of 274 MS trios where paternal transmission of three additional SNPs in this gene, rs704219, rs2041906 and rs1558793, was associated with MS (p = 0.001, p = 0.01 and p = 0.01 respectively). The gene discussed is ST8SIA1; the disease is myeloid sarcoma.