Anti-neutrophil cytoplasmic antibodies of the IgA class have been reported to occur in ulcerative colitis, autoimmune liver diseases, Henoch–Shönlein's purpura, and neutrophilic dermatoses [28-31], and RF of the IgA class has been claimed to be of clinical interest in RA [16-20]. This evidence concerns the gene CD79A and rheumatoid arthritis.