INS and type 2 diabetes mellitus: To explore the possible mechanisms of action of these variants for affecting T2D susceptibility, we tested the association of these SNPs with the T2D-related quantitative phenotypes (height, weight, BMI, WHR, insulin, creatinine, total cholesterol, LDL-cholesterol, VLDL-cholesterol, HDL-cholesterol, and triglycerides) using multiple linear regression analysis in NGT after adjusting for the effects of age, sex, BMI, disease status, and medication.