Further support to the idea that liposarcoma develops from uncommitted cells comes from the studies showing that the expression of FUS-DDIT3 in primary mesenchymal progenitor cells give rise to myxoid liposarcoma-like tumors [21], confirming that the cell type is critical for the oncogenic activity of FUS-DDIT3. The gene discussed is DDIT3; the disease is myxoid liposarcoma.