Using the same system, we showed that while the co-expression of the domain NH2-FUS did not produce any effect on the transactivation capability of C/EBPβ, the co-expression of the DDIT3 domain produced a dramatic repression in the activation of the PPARγ2 promoter by C/EBPβ, indicating that the DDIT3 domain of FUS-DDIT3 was involved in the repression of the PPARγ activity in liposarcomas by interfering with the C/EBPβ activity (Figure 4). Here, FUS is linked to liposarcoma.