TGFB1 and male reproductive organ cancer: Despite these reservations, it is of considerable interest that broccoli intervention is associated with perturbation of TGFβ1, EGF and insulin signalling, each of which has been associated with prostate carcinogenesis [31]–[35], in addition to carcinogenesis at other sites [28], [36], [37], and inflammation associated with myocardial infarction [38].