NFKB2 and B-cell non-Hodgkin lymphoma: Chromosomal translocations disrupting the Nfkb2 gene that generate truncated p100 proteins and constitutive processing of p100 to p52 were identified in cutaneous T-cell lymphoma, and, more rarely, in B-cell non-Hodgkin lymphoma, chronic lymphocytic leukemia, and multiple myeloma [9], [12], [17].