In contrast, in a study of non-small-cell lung cancer (NSCLC), the median H score for ERCC1 expression was 1.0 and 30–40% of tumours expressed ERCC1 (Olaussen et al, 2006), suggesting that the proportion and pattern of ERCC1 expression varies according to the tumour type. The gene discussed is ERCC1; the disease is non-small cell lung carcinoma.