The immune cells may even increase the potential of cancer cells to progress, proliferate, and metastasise, that is, the tumour-associated macrophages release metalloproteinases for local tissue destruction and interleukin (IL)-6 and IL-8 for endothelial cell invasion into the tumour (De Visser et al, 2006; Whiteside, 2006). Here, CXCL8 is linked to neoplasm.