STK11 and neoplasm: Previous reports have suggested the LKB1 mutation rate to be as high as 30% in NSCLC tumours and cell lines derived from patients of Caucasian origin (Carretero et al, 2004; Matsumoto et al, 2007) and to be infrequent in NSCLC patients of Asian origin (3%) (Onozato et al, 2007).