AFP and gastric neoplasm: Amemiya et al (2005) reported that c-Met overexpression was frequently detected in AFP-producing stomach cancer, whereas Kataoka et al (2001) reported that the absence of ATBF1 gene expression is responsible for AFP gene expression. Recently, Cho et al (2007) reported that five of the eight cancers with AFP expression showed genetic alterations of the ATBF1 gene.