MnSOD is overexpressed in the majority (70–80%) of ovarian cancer tissues and the level of expression of MnSOD is also positively correlated with more advanced features in ovarian cancer patients, such as tumour grade and disease progression (Ishikawa et al, 1990; Hileman et al, 2004; Hu et al, 2005). Here, SOD2 is linked to neoplasm.