Thereof 12 TFs received a high score in our T2DM set: Srebf1, Tcf2, Rela, Ybx1, Cebpb, Nr1d2, Klf10, Nfil3, Ccrn4l, Atf3, Nme1 and Drap1. Srebf1 and Ybx1 are expressed only in mouse but in every tissue. Here, NME1 is linked to type 2 diabetes mellitus.