There have been a few reports of genetic variations that are associated with NAFLD, and they have been in the genes for TNF receptor 2 (TNFR-2), TNF-α, micorosomal triglyceride transfer protein (MTP), and methylenetetrahydrofolate reductase (MTHFR) genes [6,7,26]. The gene discussed is TNFRSF1B; the disease is metabolic dysfunction-associated steatotic liver disease.