Dohanics et al., used a different stereotaxic method to compression the stalk, which resulted in marked diabetes insipidus accompanied by the significant degeneration of the AVP neuron population in both SON and the PVN, resulting in the survival of only ~35% and ~27% of AVP neurons in these nuclei at 21 days after surgery, respectively[31]. This evidence concerns the gene AVP and Central diabetes insipidus.