The mechanistic involvement of CXCL5 in the promotion of NSCLC was recently investigated in a study by Pöld et al [38], who demonstrated that enhanced tumor growth of COX-2 over-expressing tumors in a immunodeficient mouse model was associated with enhanced CXCL5 expression and inhibited by neutralizing anti-CXCL5 sera. This evidence concerns the gene CXCL5 and neoplasm.