These data correlate with FZD3/6 and WNT3 found overexpressed in other malignancies as leukaemia, FZD7 in solid tumours like nasopharynx, oesophagus, and stomach carcinomas, WNT5A in leukaemia, melanoma, and nasopharynx carcinoma (Tanaka et al, 1998; Kirikoshi et al, 2001; Holcombe et al, 2002; Weeraratna et al, 2002; Qiang et al, 2003; Lu et al, 2004; Zeng ZY et al, 2007), whereas WNT4 has been previously found overexpressed in pancreatic cancers (Pasca di Magliano et al, 2007). Here, FZD3 is linked to familial pancreatic carcinoma.