We, however, propose that in early or late infection some unclear mechanisms, e.g., cytokines or stress may affect the stability of TGF-β1, S100B, and NF-L mRNA, which attenuates their expressions in the brains of infected mice; however, this postulation and their corresponding pathophysiological functions during those periods of infection should be further tested. This evidence concerns the gene TGFB1 and infection.