To estimate the effect of Rapamycin resistant T1 cells (T1Rapa) on Wnt-1 tumor growth, irradiated and BM reconstituted mice were inoculated with tumor cells and injected either at day 5 or day 20 post transplant with 7 × 106 cells/mouse of T1Rapa cells. Here, WNT1 is linked to neoplasm.