Interestedly, several studies really supported the dysregulation of several pathways, such as Wnt signaling, MARK signaling [31,32], NF-kB-Apoptosis resistance, integrin signaling[32] in NPC although most of pathways involving cell growth and death, cell communication, and immune system, etc. have not been well documented. This evidence concerns the gene NFKB1 and nasopharyngeal carcinoma.