ATP7B and ovarian carcinoma: In previous work from our laboratory, we assessed the role of copper homeostasis proteins CTR1, ATP7A and ATP7B in uptake and efflux of cisplatin in A2780 human ovarian carcinoma cell line and its cisplatin-resistant variant A2780cis cell line as well as the relevance of these transporters for tumour cell sensitivity to cisplatin [20].