To test whether hRI influences the effects of scFv 4D5-dibarnase on cancer cells, hRI and scFv 4D5-dibarnase were incubated at a ratio of 100 units hRI to 1 μg scFv 4D5-dibarnase for 30 min at 4°C and then were added to the cells. This evidence concerns the gene EIF2AK1 and cancer.