MYC and neoplasm: In addition, genes previously identified as highly expressed in the epithelial stem/progenitor cell compartment at the base of colon crypts and in neoplastic tissue (e.g. MYB & MYC) were more highly expressed in residual tumor CoCSC than the NTG population of cells that represent the bulk of the tumor, but which are generated by CoCSC and appear more susceptible to CPA-induced cytotoxicity.