In confirmation, and to establish this applies in compound mutant Min mice, K-ras codons 12, 13 and 61 were sequenced in 27 small intestinal tumours, that included 8 tumours from ApcMin/+, K-ras+/+ mice, 15 tumours from ApcMin/+, K-rastmΔ4A/+ mice, and 4 tumours from ApcMin/+, K-rastmΔ4A/tmΔ4A mice. Here, KRAS is linked to small intestine neoplasm.