PPARD and neoplasm: In contrast to these reports suggesting that PPARδ serves as tumor accelerator, recent conflictingreports show that PPARδ deficiency enhancespolyp growth in ApcMin/+ and AOM-treated mice inthe absence of exogenous PPARδ stimulation [71, 72].Moreover, a PPARδ ligand (GW0742) inhibits colon carcinogenesis in AOM-treated mice but promotessmall intestinal polyp growth in ApcMin/+mice [73].