In prostate cancer, ratio of ω-3/ω-6 fatty acids is associated with expressions of 15LOX-1 and COX-2 [41].15LOX-1 induction by nonsteroidal anti-inflammatory drugs (NSAIDs), such assulindac sulfone, provides apoptosis in SW480 colon cancer cells. Here, PTGS2 is linked to malignant colon neoplasm.