In prostate cancer, ratio of ω-3/ω-6 fatty acids is associated with expressions of 15LOX-1 and COX-2 [41].15LOX-1 induction by nonsteroidal anti-inflammatory drugs (NSAIDs), such assulindac sulfone, provides apoptosis in SW480 colon cancer cells. This evidence concerns the gene ALOX15 and malignant colon neoplasm.