TARDBP and amyotrophic lateral sclerosis: Five of the ALS samples (ND09546, ND10023, ND09582, ND10379, ND10379) carried the synonymous variation p.A66A (c.198 T>C) in exon 2 of TARDBP, but this sequence variant was likely to be a benign polymorphism as it was found in eight of the Caucasian controls and in a single Bedouin sample of the HGDP.