PHEX and malignant colon neoplasm: In proteolysis, we identified the subtilisin PCSK2, with 4-6 fold increases in 8 of its core probe-sets in MG-thymoma and increases in colon cancer (Text S3), and the endopeptidases PHEX and ADAMTS20 (proteolysis), both up-regulated in MG-thymoma but not in colon cancer (Text S3).