HTRA1 and age-related macular degeneration: SNP rs9288410 (MAP2) on 2q35-q34 and SNP rs2014307 on 10q26 PLEKHA1/HTRA1 were also associated with AMD risk (OR: 1.92; 95% C.I.: 0.89, 4.18; P = 0.03 and OR: 0.240; 95% C.I.: 0.11, .52; P < 10-4 respectively).