Dystonia occurred during the first 2 years of the disease in 22 of 126 patients (18%) with mutations in LRRK2 compared with 5 of 21 (4%) of patients with idiopathic PD (OR 4·5, 95% CI 2·4–8·4; p<0·0001). This evidence concerns the gene LRRK2 and Dystonia.