ITGB1BP1 and infection: The filamentous-fungal specific clusters included a number of proteins that are involved in cytoskeletal rearrangements (dedicator of cytokinesis protein, integrin beta-1-binding protein, dynactin p62 family, dynein light intermediate chain 2), it seems likely that these are required for the complex morphological changes that filamentous fungi undergo during their lifecycle and the production of differentiated cells, such as spores, fruiting bodies and infection structures.