ABCA4 and brain disorder: Nominally significant (i.e. P values without correction for multiple testing) allelic associations were observed for 2 SNPs at ABCA4 (rs2997633, rs3112831) and 1 SNP at COL2A1 (rs2276455) when affected children (i.e. children with retinal or brain disease or both) in the EMSCOT cohort were compared with infected but unaffected children (Table 1).