Thus, it is intriguing to speculate that DSRCT-specific expression of ENT4, a pH-dependent (acidic) adenosine transporter, might provide growth and survival advantages to the tumor cells (e.g. by stimulating angiogenesis) under hypoxic/acidic conditions, as well as increasing the nucleoside pool within the rapidly proliferating tumor cells. Here, SLC29A4 is linked to neoplasm.