For example, the exon array data provide strong evidence (robust ANOVA F statistic: 40.5; p = 9 × 10-11) for an association between a probeset in exon 4 of the GLO1 gene, encoding an enzyme (glyoxalase I) that has been reported to show lower activity in the brains of individuals affected by autism compared to control individuals [34] and the genotype of a SNP in the same exon (C419A or rs2736654; Figure 4). Here, GLO1 is linked to autism.