GLP-1 infusion in rats resulted in myocardial pressor effects19,20 while infusion in humans after acute myocardial infarction afforded improved left ventricular function.21 Therapy for type 2 diabetics based on the actions of GLP-1 is hailed as one of the most promising recent approaches to this disease. The gene discussed is GLP1R; the disease is acute myocardial infarction.