INS and Insulin resistance: Nonetheless, even in this setting of modest overweight, a significant difference in the waist-to-hip ratio was evident between the NG and DM patients, attesting to the known importance of regional adiposity in the genesis of insulin resistance and diabetes.19,20 We were able to document positive and significant correlations between indices of adiposity, mean fasting glucose and insulin resistance (mean fasting insulin) in our hypertensive patients.