RSV G protein has been shown to modulate cytokine and chemokine production, as infection with a mutant RSV lacking the full-length G protein or the soluble part of G protein (sG) enhanced production of IL-6 and IL-8 in monocytes [6], as well as IL-8 and RANTES secretion and ICAM expression in airway epithelial cells [7]. The gene discussed is CXCL8; the disease is infection.