The injection of PLA2 (from Naja mocambique mocambique venom) in the common bile duct at 300 μg/kg (4 h) markedly increased the pancreatic plasma protein extravasation and neutrophil influx (as evaluated by the increased myeloperoxidase activity), which was accompanied by neutrophil accumulation into the lungs and elevated serum amylase levels (Table 1), thus reproducing an acute pancreatitis condition. Here, PLA2G2A is linked to acute pancreatitis.