The costs of the strategy and the costs per patient correctly identified result $1.704.161 and $2.051 for cTnI, $1.814.482 and $2.086 for cTnT, $1.608.327 and $1.890 for ex-ECG, $750.282 and $803 for ex-Echo, $525.495 and $533 for PhSE, $1.359.953 and $1.521 for ex-SPECT-Tc ($1.634 including cost of extra risk of cancer) and $5.548.794 and $29.673 for CA ($29.999 including cost of extra risk of cancer) (Figure 3) (Table 2). The gene discussed is TNNI3; the disease is cancer.