In contrast, still in comparison with Kn-HD, HOP-Penetratin did not modify apoptosis in GBM-8 cells (9.7 ± 1.31 SEM versus 7.63 ± 1.05 SEM; p = 0.24), which express low levels of HOP, or in GBM-12 cells (3.75% ± 1.4 SEM versus 3.29% ± 0.47 SEM), which express higher levels. The gene discussed is HOPX; the disease is glioblastoma.