When knocked down T47D, MDA-MB-486, MDA-MB-435s breast, LNCaP prostate and NCIH-838 lung cancer cell lines were exposed to 0.1 μM. Growth hormone-releasing hormone (1–29)NH2 the proliferation rate of the cells was strongly stimulated by 16, 132, 87, 97, 119% respectively. The gene discussed is GHRH; the disease is lung carcinoma.