These include a number of known or potential tumour suppressor genes (BCSC-1, CHEK1, ST14, ATM, P53AIP1), genes with proposed roles in cancer progression (BARX2), apoptosis (PIG8, P53AIP1) and oncogenesis (FLI1, ETS1), and a DNA damage-inducible gene (DDI1). The gene discussed is ATM; the disease is cancer.