Elevations in the levels of TXA2,its synthase or its receptor have been implicated in various cardiovasculardisorders including thrombosis, myocardial infarction, unstable angina,atherosclerosis, systemic- and pregnancy-induced hypertension and ischemic heartdisease, processes in which RhoA dysfunction is widely implicated [7]. Here, RHOA is linked to atherosclerosis.