Nevertheless, with overexpression of c-Myc in alveolar epithelium of our female transgenic mouse model resulting in the development of bronchiolo-alveolar carcinoma (BAC) and papillary adenocarcinoma (PLAC) 36 of 477 deregulated genes possess transcription factor activity or transcription regulator activity. The gene discussed is MYC; the disease is minimally invasive lung adenocarcinoma.