As previously reported in a more modestly-sized French set, T2D associations were confirmed in PPARG Pro12Ala [odds ratio (OR) = 0.81, P = 0.004], TCF7L2 rs7903146 (OR = 1.59, P = 7.9 × 10-27), and ENPP1 K121Q (OR = 1.15, P = 0.01) [7-9,11]. This evidence concerns the gene ENPP1 and type 2 diabetes mellitus.