IAPP and Insulin resistance: Human IAPP(hIAPP) is implicated in the pathophysiology of type 2 diabetes mellitus (DM2) sinceit forms proteinaceous tissue deposits in the pancreatic islets (“islet amyloid”) [1–3].Islet amyloid has been demonstrated in more than 80% of patients with DM2 [4, 5].Islet amyloid formation is implicated in development of beta cell failure which,in addition to insulin resistance, is a characteristic of DM2 [6].