In addition, in order to characterize moesin and P-moesin expression and distribution in invasive breast cancers, we stained samples from human ductal carcinomas (tumor stage: pT1c–node size between 1 and 2 cm-see Table 1) and we compared the pattern of staining of ER positive or negative cancers, with or without lymph node metastasis. This evidence concerns the gene ESR1 and neoplasm.