The median blastemal, stromal and epithelial cyclin E SI were also higher in nephroblastoma with metastases: 88% (range, 60%–95%), 55% (range, 29%–84%) and 51% (range, 47%–60%) respectively versus 34% (range, 6%–90%), 24% (range, 5%–69%) and 30% (range, 8%–80%) in nephroblastoma without metastasis. Here, CCNE1 is linked to Wilms tumor.