MYC and adenocarcinoma: The gene encoding c-MYC is located within chromosomal region 8q23–24.2, a region frequently amplified in adenocarcinomas of the oesophagus and gastro-oesophageal junction and that has been detected in Barrett's metaplasia (Walch et al, 2000; Croft et al, 2002; Doak et al, 2003; van Dekken et al, 2006).