EGFR and central nervous system cancer: The set of overexpressed genes in gliomas with EGFR amplification was significantly enriched in genes located on chromosome 1 (305 genes, p < 10-4), chromosome 19 (151 genes, p < 10-4), chromosome 7 (109 genes, p < 10-4) and chromosome 4 (85 genes, p < 10-4).