IFNG and chlamydia trachomatis infectious disease: Previous evidence suggests that the concurrent immunization with cHSP60 switches the cytokine production of self HSP60 responding T cells to dominant production of proinflammatory IFN-γ [46] showing that chlamydial HSP60 can break the tolerance of autoreactive cell reactions and lead them to participate in the inflammatory reactions during chlamydial disease.